- Shelley Winters (2 films)
- Shelley Duvall (1 film)
- Shawnee Smith (2 films)
- Shawn Wayans (1 film)
- Shawn Dou (1 film)
- Shawn Ashmore (2 films)
- Shauna Macdonald (1 film)
- Shaun Thomas (1 film)
- Shaun Evans (1 film)
- Shaun Benson (1 film)
- Sharon Stone (2 films)
- Sharon Horgan (1 film)
- Sharon Farrell (1 film)
- Sharon Ceccatti (1 film)
- Sharlto Copley (7 films)
- Shari Finkelstein (1 film)
- Shari Eubank (1 film)
- Shaofeng Feng (1 film)
- Shantel VanSanten (1 film)
- Shane McRae (1 film)
- Shane Carruth (1 film)
- Shamon Brown Jr. (1 film)
- Shamier Anderson (1 film)
- Shameik Moore (2 films)
- Shakira (1 film)
- Shaine Jones (1 film)
- Shaïn Boumedine (1 film)
- Shailene Woodley (2 films)
- Shaheizy Sam (1 film)
- Shahadi Wright Joseph (1 film)
- Seth Rogen (16 films)
- Seth Meyers (1 film)
- Seth MacFarlane (4 films)
- Seth Green (1 film)
- Sergio Peris-Mencheta (2 films)
- Sergi López (2 films)
- Sergej Trifunović (1 film)
- Serge Swysen (1 film)
- Serge Sauvion (1 film)
- Serge Riaboukine (2 films)
- Serge Hazanavicius (1 film)
- Sepideh Farsi (1 film)
- Senan Jennings (1 film)
- Semen Serzin (1 film)
- Selma Blair (1 film)
- Selena Gomez (5 films)
- Sela Ward (1 film)
- Seidi Haarla (1 film)
- Sehar Bhojani (1 film)
- Sedona Legge (1 film)
